Chromatography systems

Biorad chromatography

Chromatography systems 

Most chemical processes involve the separation of chemicals from a complex mixture.  Equally, recovering proteins inevitably requires some sort of purification step, whether extracting them from a waste stream, such as liquid dairy wastes or brewery residues, or from a fermentation specifically designed to produce target proteins.

We have a wealth of knowledge and experience in the extraction and clean-up of proteins using a range of chromatographic techniques including ion exchange, affinity chromatography, hydrophobic interaction and gel filtration with three chromatography systems that allow us to work at different scales depending on the customer need.

The AKTA Pure-25 protein purification system (0.001-25 mL per minute) is for fast purification of proteins, peptides, and nucleic acids from microgram to gram levels of target product.

The BioRad Chromatography Skid is designed for the small-scale production/purification of pharmaceuticals or proteins. It has a column diameter of 100 mm and flow rates of between 5-120 L/hr.

The Biotage Isolera LS system is a flash purification system designed for the separation of complex organic mixtures. It has cartridges instead of a column which are typically pre-packed. The flow rate of the Isolera system is 5-400 mL/min.

To use the chromatography systems or find out more about its capabilities, please contact us.

We have an extensive range of downstream processing equipment, see below.

Downstream processing

Analytical equipment

Analytical equipment

We have a variety of analytical equipment available at the centre.

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Counter current liquid-liquid separator/contactor

Counter current liquid-liquid separator/contactor

Our CINC counter current liquid-liquid separator allow liquid/liquid separation of two phases of differing density.

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Chromatography systems

Chromatography systems

Used for purification and separation of complex organic mixtures.

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Distillation and evaporation

Distillation and evaporation

Our Centritherm® (CT01-9RM) evaporator is one of our distillation units, which is particularly suitable for concentration of materials at relatively low temperatures.

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Flavourtech spinning cone

Flavourtech spinning cone

We have a larger version of the Centritherm evaporator, the Flavourtech Spinning Cone, capable of handling up to 1 ton/h of material. The flavourtech spinning cone is a thin-film distillation column, consisting of 21 inverted cones.

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Gas chromatography

Gas chromatography

Gas chromatography (GC) is a flexible technique that allows separation and quantification of chemical substances found within a complex mixture.

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Pilot-scale continuous centrifuges

Pilot-scale continuous centrifuges

We have two pilot scale continuous centrifuges, capable of operating (depending on feedstock) at process feedstocks rates of up to 100 L/h.

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Ultrafiltration and filtration

Ultrafiltration and filtration

We have several filtration units available at the BDC.

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